Protocol

Coronary artery calcium (CAC) scoring

CT calcium score · Calcium score · CAC score · Cardiac calcium scan · Coronary calcium scoring · Agatston score

CAC is the best-evidenced item in the longevity imaging category, but the evidence is prognostic rather than interventional. Everlab cites the Multi-Ethnic Study of Atherosclerosis (Detrano et al., NEJM 2008), a large prospective cohort showing CAC independently predicts future cardiovascular events. That design is observational, not randomised: it establishes that the score stratifies risk, not that scanning asymptomatic people improves survival or healthspan. There is no live-verified randomised trial evidence retrieved here showing that CAC screening itself reduces mortality, and a zero score does not exclude non-calcified plaque. Note a correction to the discovery brief: the National Heart Foundation of Australia endorsement attributed to Everlab could not be found on either Everlab page retrieved; both the imaging page and the test index omit it, and the imaging page cites MESA instead. Treat the Heart Foundation attribution as unverified pending a direct Heart Foundation source.

At a glance

Evidence
Clinical
Singapore (HSA)
Not an HSA-registered product. CAC scoring is a radiological procedure, not a therapeutic good. HSA's remit, per its own medical devices page, covers "the import, manufacture, export and supply of medical devices in Singapore" — that is, the CT scanner as a device, not the clinical test performed on it. No HSA registration, approval or restriction specific to coronary calcium scoring was found. Clinically it is offered in Singapore as a paid add-on, not a core screening inclusion: NOVI Health lists "CT coronary calcium score^ - $381.50 w/GST" as an add-on outside its three tiered packages.
Australia (TGA)
No TGA position on file
Offered at
2 clinics

Singapore

Health Sciences Authority

HSA status
Not an HSA-registered product. CAC scoring is a radiological procedure, not a therapeutic good. HSA's remit, per its own medical devices page, covers "the import, manufacture, export and supply of medical devices in Singapore" — that is, the CT scanner as a device, not the clinical test performed on it. No HSA registration, approval or restriction specific to coronary calcium scoring was found. Clinically it is offered in Singapore as a paid add-on, not a core screening inclusion: NOVI Health lists "CT coronary calcium score^ - $381.50 w/GST" as an add-on outside its three tiered packages.
In our SG set
Tracked in Singapore
SG clinics
1

Australia

Therapeutic Goods Administration

TGA status
No position on file
In our AU set
Tracked in Australia
AU clinics
1
Evidence is not approvalAn evidence grade describes how strong the science is. A regulatory status describes whether a body has approved the intervention for an indication. They are different questions, answered separately above.

What it is

Plain-language explainer

Coronary artery calcium scoring is a non-invasive cardiac CT scan that quantifies calcified atherosclerotic plaque in the coronary arteries, reported as an Agatston score. Everlab describes it as "a non-invasive heart scan that uses specialised X-rays to measure the amount of calcified plaque in your coronary arteries." It is used to refine cardiovascular risk estimates in people without symptoms, particularly where standard risk calculators place someone in an intermediate band.

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Protocol

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Where variis has verified this protocol (2)

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